After two years, Sabina Jeschke became a junior professor for New Media in Mathematics and Natural Sciences at the Technische Universität Berlin.

[6] Additionally she was a visiting professor and head of the former Center for Multimedia in Teaching and Research (MuLF) now innoCampus at the Technische Universität Berlin.

[7] In 2009 she followed the call of the RWTH Aachen University and became a professor and the director of the Institute Cluster IMA/ZLW & IfU[2] at the Faculty of Mechanical Engineering.

[8] Until 2010 she additionally functioned as a visiting professor with scientific direction of research projects at the Institut für Technische Optik (ITO) of the University of Stuttgart, Germany.

[10] Some of the main areas of her research are robotics and automation technology (heterogeneous and cooperative robotics, web services in robotics), traffic and mobility (autonomous and semi-autonomous transport systems, international logistics, car2car & car2X models), Internet of Things and cyber-physical systems (industry 4.0, semantic web services), Artificial Intelligence (data integration and data mining, multi-agency systems, cognitive computing), human-machine interaction (virtual and remote laboratories, intelligent training environments), innovation research (innovation fields, trend monitoring) and information management (integration technologies for information services, innovative learning and teaching concepts).

Jeschke took a sabbatical during the 2017 summer semester to focus on her research in artificial/machine consciousness and was involved establishing the Strong Artificial Intelligence think tank at Volvo in Gothenburg, Sweden.

[14] On 18 February 2021 Jeschke announced her intention to terminate her Management Board contract prematurely on 31 May 2021 "at her own request and on the best of amicable terms".

In her latest project ComplAIzer, she is dedicated to the complex and constantly changing legal compliance requirements in order to simplify processes in companies through the use of AI.