Sabina Orellana Cruz (born 1970) is a Bolivian unionist and politician of Quechua origin who served as Minister of Cultures, Decolonization and Depatriarchalization under President Luis Arce from 2020-2024.

From 1993 to 2004, Orellana worked as a reporter for Radio Chualake dealing with issues of the environment, municipalities, education, health, and gender.

On 20 November 2020, President Luis Arce restored the Ministry of Cultures and Tourism which had been dissolved by the previous administration of Jeanine Áñez on 4 June.

In addition, Orellana declared that during her tenure in the ministry, she would work to promote the Wiphala as a national symbol, regretting that it had been burned during the 2019 crisis after the resignation of the president Evo Morales.

[7] On 19 May 2021, Orellana publicly asked the Ministry of Foreign Affairs of Bolivia to proceed to cut Bolivia–United States relations, claiming that the government in Washington "attacks Bolivian sovereignty".