From 2003 to 2010, Monauni was the deputy head of the EEA staff unit of the Liechtenstein government in Vaduz.

[2][3] In August 2020 she was announced as the Progressive Citizens' Party's candidate for Prime Minister of Liechtenstein, being the first female to do so.

[5] As a result, the Progressive Citizens' Party and the Patriotic Union formed a coalition under Daniel Risch as prime minister, with Monauni serving as Deputy Prime Minister of Liechtenstein since 25 March 2021.

[7] In August 2024, she was announced as a government candidate in the 2025 Liechtenstein general election.

[8] She married Gian-Reto Monauni (born 5 April 1968) on 27 March 2009, and they have two children.