Sacca Sessola is one of the biggest islands in the lagoon, with an area of 16.03 ha (40 acres), and also one of the youngest.

[1] The entire island now houses the JW Marriott Venice Resort and Spa[2] The island was built in the southern part of the Venetian Lagoon from 1860 to 1870 using debris generated by commercial port construction at Santa Marta in Venice.

In 1929, the municipality donated the island to the National Institute for Social Security, which expanded and repurposed the hospital as a pulmonological facility.

Ownership reverted to the Venetian municipality in 1982, which in turn donated it to the UNESCO International Center for Marine Sciences and Technology ten years later.

[1] In 2000, the island was sold to a multinational company and converted into a luxury hotel complex, which failed to open.