Safa Giray (Crimean Tatar, Persian, and Ottoman Turkish: صفا کرای) was three times khan of Kazan (1524–31, 1535–46, 1546–49).
The matter was settled when a faction deposed Safa Giray and enthroned the pro-Russian Jan Ali.
Second reign 1535–46: Four years later, in 1535 the Kazan nobility expelled or killed the pro-Russian Jan Ali and Safa Giray returned to the throne.
In 1546 a Kazan faction revolted and Safa Giray fled to his father-in-law Yusuf of the Nogai horde.
In late 1547 Ivan the Terrible in person led a winter campaign against Kazan, but an early thaw made the roads and rivers impassible, so he returned to Moscow.