In a research career spanning more than half a century, Bose published 120 papers on various aspects of fungi in an array of academic journals across Europe, America, and Asia.
In 1918 he went to Ceylon (now Sri Lanka) on a deputation to the Royal Botanical Gardens, Perudeniya for training in systematic of Bengal Polyporaceae (bracket fungi) under the famous mycologist Tom Petch.
Bose's paper on "the spore- forming bacterium on rice grains" in Lancet in May 1924 refuted the old "rice-toxin" theory of Knowles, Acton and Chopra.
He proved with the help of P.W.Wilson of Wisconsin University that, contrary to prevailing view, Phoma casuarinae did not fix nitrogen directly from the air.
One of the crowning achievements of Bose was his discovery of two antibiotics obtained from higher fungi, polyporin from Polistictus sanguineus and campestrin from Psalliota campestris, which were not concentrated.