Saint-Chrysostome (French pronunciation: [sɛ̃ kʁizɔstom]) is a municipality in south-west Quebec, Canada in the regional county municipality of Haut-Saint-Laurent in the Montérégie administrative region.

The municipality was created by the amalgamation of Saint-Chrysostome village with the parish of Saint-Jean-Chrysostome on September 29, 1999.

In addition to the namesake main population centre, the following locations reside within the municipality's boundaries:[1] The following waterways pass through or are situated within the municipality's boundaries:[1] In 1800, the area was surveyed and assigned the name Russelltown, after Russell Ellice, son of Lord Alexander Ellice who then owned the Seignory of Beauharnois.

[1] In 1843, the parish of Saint-Jean-Chrysostome(-de-Russelltown), named in honour of John Chrysostom, was created when it separated from Sainte-Martine.

The municipality was reestablished on July 1, 1855, and changed name and status in August 1858 to become the Parish Municipality of Saint Jean Chrysostome (orthography was adjusted to include hyphens in 1969).