Sainte-Barbe (French pronunciation: [sɛ̃t baʁb] ⓘ) is a municipality of Quebec, located within Le Haut-Saint-Laurent Regional County Municipality in the Montérégie administrative region.

The population as of the Canada 2021 Census was 1,609.

Sainte-Barbe was created on January 1, 1883, by splitting away from Saint-Anicet.

The name honors Saint Barbara and pays homage to Marie-Barbe de Boullongne (1618-1685), wife of Louis d'Ailleboust de Coulonge, governor of New France.

The following locations reside within the municipality's boundaries:[1] The following waterways pass through or are situated within the municipality's boundaries:[1] Media related to Sainte-Barbe, Quebec at Wikimedia Commons