Saint-Eugène-de-Ladrière (French pronunciation: [sɛ̃t‿øʒɛn də ladʁijɛʁ]) is a parish municipality in the Rimouski-Neigette Regional County Municipality in the Bas-Saint-Laurent region of Quebec, Canada.

On July 6, 2002, unorganized territory Grand-Lac-Touradi was annexed by Saint-Eugène-de-Ladrière.

The first parish priest was Oscar Thibeault from 1959 to 1968.

The municipality of Saint-Eugène-de-Ladrière was therefore created the same year by splitting from Saint-Fabien.

Saint-Eugène-de-Ladrière is located 35km southwest of Rimouski and 40km from Saint-Anaclet-de-Lessard.