Saint-Germain-de-Grantham is a municipality in the Centre-du-Québec region of Quebec.

The population as of the Canada 2021 Census was 4,922.

Saint-Germain-de-Grantham was the birthplace of Marie Rose Ferron.

[5] Population trend:[6] Mother tongue language (2021)[7] Saint-Germain-de-Grantham's main transportation link is Autoroute 20 which travels through most of Québec on the southern side of the St. Lawrence River.