Saint-Joseph-de-Lepage (French pronunciation: [sɛ̃ ʒozɛf də ləpaʒ]) is a parish municipality in La Mitis Regional County Municipality in the Bas-Saint-Laurent region of Quebec, Canada.

Saint-Joseph-de-Lepage takes its name from the colonial lordship, the Seigneurie Lepage-et-Thibierge, which was the early governance of the area.

The territory occupied by the parish municipality of Saint-Joseph-de-Lepage was first granted to Gabriel Thivierge and Louis Lepage and became known as the seigneury of Lepage-et-Thivierge.

Later, this seigneury became the Seignory of Rimouski, which for a long time belonged to the Lepage family.

The municipality of Saint-Joseph-de-Lepage was officially created on 29 September 1873 by a detachment from Sainte-Flavie.