Saint-Luc-de-Bellechasse (French pronunciation: [sɛ̃ lyk də bɛlʃas]) is a municipality in the Municipalité régionale de comté des Etchemins in Quebec, Canada.

It is part of the Chaudière-Appalaches region and the population is 485 as of 2009.

Originally named Saint-Abdon, it was changed to Saint-Luc-de-Dijon, due to confusion in spelling and difficulties of pronunciation.

Saint-Luc honours Luc Gilbert of Saint-Augustin-de-Portneuf, who would have given an important sum for the construction of the rector.

The source of the Etchemin River is in Saint-Luc-de-Bellechasse.