Saint-Priest-la-Marche (French pronunciation: [sɛ̃ pʁijɛ(st) la maʁʃ]) is a commune in the Cher department in the Centre-Val de Loire region of France.

A farming area comprising the village and several hamlets situated by the banks of the Indre, about 48 miles (77 km) south of Bourges at the junction of the D203 with the D3e road.

It is the southernmost commune of the department and borders the departments of Indre and Creuse.