Pope Callixtus III (1455–1458) gave the church of St. Andrea de Mortarariis to the Breton community in Rome.

The church was pulled down and rebuilt in 1878 by Luca Carimini in Neo-Renaissance style.

The maintenance of the old apse, would coincide with the current chapel of the Blessed Virgin (Santa Vergine).

The persistence of the masonry structure of the apse, with its proportions, would have affected the plan and the elevation development.

The 90 ° rotation of the axis of the church (necessary for obtaining a building of smaller dimensions in the same lot), would have required the construction of a symmetric chapel, equally great.