Ana (Serbian Cyrillic: Ана); fl.

June 22, 1200) was the princess consort of the Serbian Principality as the wife of Stefan Nemanja (r. 1166–1196).

She is venerated by the Serbian Orthodox Church as Saint Anastasija (Serbian: Света Анастасија / Sveta Anastasija) with her feast day on June 22 (Julian calendar).

The earliest source mentioning her origin was Domentijan (c. 1210 – after 1264), who said of her: "a great princess, daughter of the Byzantine Emperor Romanos", only Romanos IV Diogenes ruled 1068–71, making this genealogy impossible.

Through the marriage with Stefan Nemanja, they had three sons and three daughters: