Originally built in 1831, it is oldest Catholic Church in the state to have continually occupied the same building.
Monthly mass began in 1847, and during the 1860s the church was one of few to not be destroyed during the American Civil War.
Stained glass windows from an Ursuline convent were moved to Saint Andrew's.
The rear of Saint Andrew's is surrounded by a cemetery, which holds the graves of several prominent local figures.
This article about a church or other Christian place of worship in South Carolina is a stub.