John Moore (June 27, 1835 – July 30, 1901) was an Irish-born prelate of the Catholic Church who served as the second Bishop of St. Augustine from 1877 to 1901.

A contingent of Benedictine monks arrived in San Antonio, Florida, in 1886, initially to serve German immigrants.

At Moore's request, a group of Jesuit fathers arrived in Tampa, Florida, in 1888 to replace the priests lost to illness.

With the local priest, Reverend William John Kenny, sidelined by the disease, Moore rushed there to run the parish and tend to the sick.

[2] In 1889, Moore asked the Benedictines to establish several mission churches on the Florida Gulf Coast from Pasco County northward.