His life is dated to the first, second, fourth, and fifth century by various sources since he is often confused with various other venerated Antonini.

Today he is revered as the patron saint of Pamiers, Palencia, and Medina del Campo.

Reportedly born at Fredelacum (Pamiers), Antoninus converted to Christianity and made a pilgrimage to Rome, where he was ordained.

According to local tradition, the Crypt of Saint Antoninus [de] at Palencia Cathedral, which supposedly houses his relics, was finished during the mid-seventh century episcopate of Ascaric.

It claimed to possess his head and part of his body, brought from Syria by a boat that had navigated the rivers Ariège, Tarn, Garonne, and Aveyron with the aid of an angel.