However, as Martin Davies writes, "S. Crescentino’s story, so far as I am aware, excludes a Princess or other female victim.

To escape the persecutions of Diocletian, he fled to Umbria, and found refuge at Thifernum Tiberinum (present-day Città di Castello).

Wishing to enrich his cathedral, Blessed Mainard (Mainardo), the Bishop of Urbino, brought the saint's relics to the city in 1068.

[1] The coin known as the armellino (popularly called the volpetta) issued by the Duke of Urbino, Francesco Maria I della Rovere, featured Saint Crescentinus on horseback.

Another ritual involves tapping devotees’ heads with Crescentinus' relics, to free the supplicant from headaches.