Since then the church is empty, is deprived of the parish; even the fact it belonged to the Holy Throne is being forgotten".

In 1795 Agha Mohammad Khan forces enter the city and completely destroy the district of Sulfuric Baths.

After entering Russian Empire Tbilisi became governmental center and started rapidly develop.

In 1831 Manuel Kyumushkhanetsi from the Crimean Peninsula was appointed the Archpriest of the church and started complete reconstruction and restoration in short time entering list of functioning Armenian churches.

In 1910s Tirayr Ter-Hovhannisyan, famous Armenian churchman, poet, philologist and translator served as vicar here.