Sal N. DiDomenico is an American state legislator who has served in the Massachusetts Senate since May 2010 and as Assistant Majority Leader since 2018.

[3] He is a Democrat representing the Middlesex and Suffolk district, which includes his hometown of Everett as well as Chelsea, Charlestown, and parts of Cambridge.

He attended Cambridge Rindge and Latin School before continuing his education at Boston College, where he earned a bachelor's degree in Business Administration in 1997.

After Anthony Galluccio abruptly resigned in 2010, DiDomenico quit the office to run for Massachusetts State Senate.

DiDomenico has filed many major pieces of legislation focusing on community development, education, children's health, election laws, human services, and public safety.