[1] Mazari was born in Iran in 1980,[2][3] a refugee as her family had escaped the Soviet invasion of Afghanistan.

[4] She grew up in Iran, earning a degree from the University of Tehran and working for the International Organization for Migration, before returning to Afghanistan.

As governor, she formed a security commission to recruit local militias into the fight against the Taliban.

Until the complete collapse of the Islamic Republic of Afghanistan following the Fall of Kabul, hers was one of the few districts in the country to remain unoccupied by the Taliban.

[9][10][11] As per subsequent Time.com news report, Mazari was at provincial Governor's office when news of the surrender of Balkh and fall of Mazar-i-Sharif reached her, after realizing her district Charkint, too is blocked she decided to close fight to avoid blood bath and escaped to undisclosed U.S. location with the help of 2021 U.S. evacuation from Afghanistan[11] She was recognized as one of the BBC's 100 Women of 2021.