The salinosporamides are a group of closely related chemical compounds isolated from marine bacteria in the genus Salinispora.
[1][2][3][4] They possess a densely functionalized γ-lactam-β-lactone bicyclic core.
Salinosporamide A has attracted interest for its potential use in treating various types of cancer.
[5][6][7][8] In addition, a variety of synthetic analogs have been prepared.
[9]