Known for her beauty and wit,[1] Mrs. Otis was the acknowledged "queen of Boston society"[2] of her time, attending parties and, along with her husband, playing host to prominent Bostonians and visitors to the city.

[4] Foster married Harrison Gray Otis on May 31, 1790, at the age of 20.

As Mrs. Otis, she took on the role of managing their large home and playing hostess to frequent parties because of her husband's public status.

She exercised a great interest in French culture, manners, and fashion.

[3] Otis died September 6, 1838, at the age of 68, at their residence on Beacon Street in Boston.