Salome Sellers (née Sylvester; October 19, 1800 – January 9, 1909) was an American centenarian who was the last known, verified person born in the 18th century.

Descending from Mayflower Stock (she was a great-great-great-granddaughter of John Howland and great-great-great-great-granddaughter of Isaac Allerton) her father served during the American Revolution.

Sellers died in the same house she and her husband had built in 1830 in Deer Isle, Maine on January 9, 1909, aged 108 years, 82 days.

and written by Caroline Smith Rittenhouse that details her life: "An Island Woman: Salome Sylvester Sellers, Deer Isle, Maine 1800–1909".

At the time of her death, she was the oldest woman in Maine and possibly the United States.