Salvatore Monosilio was an Italian painter of the 18th century, active in a late-Baroque style in Rome.
He remained in Rome, painting the ceiling of a chapel in the church of San Paolo alla Regola.
For the School of the Padre Pie, he painted a St Giuseppe Calasanzio receives stigmata.
He restored some portraits of popes in the Vatican collections under the direction of the canon Marangoni.
He sent to Messina two canvases for the Jesuits and a depiction of the titular saint for San Andrea Avellino.