After Michigan, he studied writing at Columbia University in the Master of Fine Arts program.
Apple is the author of Ravenous: Otto Warburg, the Nazis, and the Search for the Cancer-Diet Connection.
Liveright editor Robert Weil solicited the book after reading one of Apple's articles in The New York Times Magazine.
Apple is on the faculty of the MA in Science Writing program at Johns Hopkins University.
Apple was editor of New Voices magazine, director of interactive media at Nerve.com, and publisher of The Faster Times.