He is best known as a member of the sketch comedy troupe The Whitest Kids U' Know, founded by Trevor Moore, Zach Cregger, and himself.

While attending Sandwich High School, Brown made a movie for his calculus class as part of a group.

[1] While working New York City comedy clubs, he met Trevor Moore, who also attended SVA and lived in the same dormitory.

[1] The two decided to start a comedy troupe, joined shortly thereafter by mutual friend Zach Cregger.

In 2008, Brown and Williams guest-starred in an episode of the Adult Swim series Fat Guy Stuck in Internet.