Sexton started his professional career in September 2005, in his home town of Norwich when he defeated Paul Bonson over six rounds at Carrow Road.

"[4] Following the tournament Sexton returned to the ring in November in order to challenge for his first professional title belt, the Southern Area Championship.

Rogan cited a neck injury preventing him using his left arm when interviewed afterwards, as the reason for being pulled out by his corner.

[7] On 13 February 2010, Sexton was due to fight Danny Williams for the British title at Wembley Arena but had to pull out with a hand injury.

The fight was rearranged for May but Sexton pulled out after his mother suffered a brain aneurysm and was replaced by Derek Chisora.

On 19 May 2012, at Aintree Racecourse in Liverpool, Sexton was defeated by David Price by a fourth-round KO, in a fight for the vacant British and Commonwealth heavyweight titles.

[10] On 6 October 2017, Sexton defeated Gary Cornish by unanimous decision and won the vacant British title at the Meadowbank Sports Centre, Edinburgh.

[11] On 14 February 2018, Hennessy Sports along with Infinitum announced that Sexton would make his first defence of the British heavyweight title at Macron Stadium's Premier Suite in Bolton on 12 May against Hughie Fury, live and exclusive on Channel 5.

Speaking of the fight, Mick Hennessy said, "I'm delighted to bring the historic British Heavyweight Championship back to mainstream, free-to-air, television on Channel 5 where it will be seen by the biggest viewing audience possible due to their considerable reach and exposure.