She is best known for producing the acclaimed films The Florida Project, Red Rocket, and the Palme d'Or winning Anora, which received six nominations at the 97th Academy Awards.

She received praise for her theatre role as Huong in the stage play Poor Yella Rednecks by Qui Nguyen.

[12] In 2025, Quan won a PGA Award for producing Anora alongside Baker and Alex Coco.

[14] Quan won the Critics Choice Association's Celebration of Asian Pacific Cinema and Television Producer Award for her work on Anora.

[15][16] At a press conference at Cannes Film Festival, Mikey Madison said that Baker and Quan would act out different sex positions to demonstrate what they wanted the actors to do.