She has played a range of characters in various series and films, in multiple languages including Tamil, Telugu, Punjabi, Hindi and Kannada.

[1][2][better source needed] Samiksha later relocated to Mumbai to pursue a career in acting and eventually became a director and a producer at SSO Production.

Months later, she subsequently appeared in the 2005 Tamil film Arinthum Ariyamalum,[4] where she starred opposite Navdeep and Arya.

Samiksha, alongside film work, made her television debut on Sahara One's Zaara – Pyaar ki Saugat, in the titular role.

[8] From 2017 to 2018, she portrayed Olympias in Sony TV's historical drama Porus opposite an ensemble cast of Laksh Lalwani, Rohit Purohit and Rati Pandey.