[1] Following the victory of the Syrian revolution, al-Masry appeared in a self-recorded video where he celebrated the victory with tears, emotionally describing how he was coming to see his mom who he had not seen for 14 years due to the exile imposed by the Assad regime after he received numerous threats for voicing opposition to the now ousted regime.

[2][3]On January 26, 2025, Al-Masry arrived in Damascus airport where he was welcomed by supporters and went and visited his mom for the first time in 14 years.

He has also starred in Orkedia, Jalsat Nisaa'ya, Al Dabour, 'Wajh El Adalah', Abu Janti, and Beit Jidi.

In 2014, Samer Al-Masry took part in the new movie From A to B alongside Egyptian actor Khaled Abol Naga and Yosra El Lozy.

In 2016, Al-Masry starred in the movie 'The Worthy' and The Cell in 2017 along with Egyptian actors Ahmed Ezz and Amina Khalil.