Miawpukek First Nation is a Mi'kmaq First Nations band government in Conne River, Newfoundland and Labrador, Canada, with a registered population of 836 living on-reserve as of May 2023, with another 2,265 living off-reserve.

[5][6] They control the reserve of Samiajij Miawpukek in Bay d'Espoir on the island of Newfoundland.

[7] Samiajij Miawpukek was established as a federal Indian reserve in 1987, the first in Newfoundland and Labrador.

Due in part to increased education of its members, it has gone on to become the most well-off First Nation in Atlantic Canada after Membertou.

[10] In 2019, the Miawpukek First Nation opened the "Cannabis Boutique", which they claim is "the first Indigenous-owned and -operated marijuana store in Newfoundland".