He is founder of two religious Collections, co-editor of the "Coptic Encyclopedia" and co-director of the magazine "Parole de l’Orient".
He serves on various publications editorial boards, and regularly comments on important events in the Middle East and the Muslim world in the online magazine "AsiaNews".
In 1975, Samir was appointed professor at the Pontifical Oriental Institute (Rome), teaching there for over 39 years, and advising numerous doctoral students in the field of Arab Christianity.
Attendance at the rich libraries of Europe also allowed him to gather, in microfilm format, a large collection of manuscripts of Christian Arab authors.
In 2018, he returned to Egypt, to continue the work he started 50 years earlier at the Christian Arab Research Center in Cairo.