Shah's research has focused on improved management of patients with common childhood infections, particularly pneumonia and meningitis.
[1] Upon completing his medical residency and fellowships, Shah became an assistant professor of pediatrics and epidemiology at the Perelman School of Medicine at the University of Pennsylvania and an attending physician at Children's Hospital of Philadelphia.
He also received research support from the Robert Wood Johnson Foundation Physician Faculty Scholar Program from 2008 until 2011 where he worked on his project "Predicting Adverse Outcomes in Children with Community-Acquired Pneumonia.
[7] In January 2019, Shah was appointed Editor-in-Chief of the Journal of Hospital Medicine,[8] having previously served as the Clinical Review and Education Editor for JAMA Pediatrics and as a founding associate editor of the Journal of the Pediatric Infectious Diseases Society.
[10] While serving as Editor-in-Chief, Shah oversaw the Clinical Guideline Highlights for the Hospitalist[11] and earned the Academic Pediatric Association's Research Award.