Samuel Cabot Jr. (December 21, 1784 – September 2, 1863) was an American businessman in the early-nineteenth-century China Trade, a member of the wealthy and prominent Cabot family.

[4] In 1806, after a couple of years familiarizing himself with the East Indies trade, he set up business in Philadelphia, in partnership with Samuel Hazard.

[5][6] After marrying Eliza, Samuel then went into business with his brother Joseph and with John W. Perit, taking charge of the Philadelphia-based partnership's Boston office.

[7] He entered the China Trade in 1817, in yet another family partnership, with his Perkins in-laws.

[9] Together, they lived in Brookline, Massachusetts and were the parents of seven sons, including:[10][11] Cabot died on September 11, 1863.