Samuel Desjardins (July 25, 1852 – December 4, 1924) was a Canadian politician.

Born in Ste-Thérèse, Canada East, the son of Samuel Desjardins and Sophie Laurier, Desjardins was educated at the College of Ste-Thérèse de Blainville.

A physician, He was first elected to the House of Commons of Canada for the electoral district of Terrebonne in a 1903 by-election held to fill the vacancy caused by Raymond Préfontaine choosing to sit for the riding of Maisonneuve, after having been elected in the two constituencies.

A Liberal, he was re-elected at the general elections of 1904 and was defeated in 1908.

This article about a Quebec Member of Parliament from the Liberal Party of Canada is a stub.