[2][3][4] Born in Monterrey, Nuevo León, García has an extensive academic background, holding three doctoral degrees: one in public policy and public administration from the Monterrey Institute of Technology and Higher Education (ITESM), in tax law from ITAC University, and in constitutional law and governance from the Autonomous University of Nuevo León (UANL).

García was elected governor of Nuevo León in 2021, defeating the Institutional Revolutionary Party nominee, Adrián de la Garza, by 10.21%.

In 2023, García secured the Citizens' Movement presidential nomination for the 2024 election, but withdrew amidst a political crisis over the appointment of an interim governor in Nuevo León.

His father was from Guardados de Abajo, Tamaulipas, who moved to Nuevo León to study law at the age of 14, eventually becoming a lawyer and prosecutor.

[7] García hosted a children's newscast on Canal 28 Nuevo León, a state-owned TV channel, where he conducted interviews and would conclude the program with readings on religious topics, taken from his mother's books.

[13] In 2017, he assumed provisional leadership of the Citizens' Movement party in the state of Nuevo León, succeeding Pilar Lozano Mac Donald [es].

In October 2018, he travelled to The Hague as part of the Mexican Senate's appeal against the former governor of Veracruz, Javier Duarte de Ochoa, on charges of crimes against humanity before the International Criminal Court.

He asserted that he possessed substantial evidence, referencing four judgments from the Electoral Tribunal of the Federal Judiciary (TEPJF) that purportedly implicated Jaime Rodríguez Calderón in these illicit activities.

[20] For the LXIV Legislature of the Mexican Congress: On 15 November 2020, Citizens' Movement announced that García and local deputy Luis Donaldo Colosio Riojas were seeking the party's gubernatorial nomination.

[23] On 5 March 2021, García kicked off his campaign at a conference where he unveiled proposals for a new tax agreement, a new vaccination plan funded with private investment, a new public transport system, a new infrastructure program, an intensified fight against corruption, and a new regional airport hub.

Taking advantage of industrial firms seeking to move their supply chains from China to Mexico, García has spearheaded the nearshoring trend, with the governor frequently traveling abroad to negotiate with business leaders.

[45][46] García included four types of environmental taxes in the 2022 budget: on contamination from stone material extraction, and on pollutant emissions into the atmosphere, water, and soil.

[50] García faced criticism for the deforestation of parts of the Santa Catarina River [es], which he defended as a preventive measure against potential hurricane-induced flooding;[51][52] the project was halted due to opposition.

[66] García proposed his Master Road Plan, which aimed to enhance state connectivity and facilitate direct access to the Laredo–Colombia Solidarity International Bridge.

In early April 2022, Texas Governor Greg Abbott announced heightened inspections of commercial trucks entering from Mexico,[81] causing significant traffic delays at the border.

García met with Abbott and signed an agreement, committing to increasing security and establishing checkpoints on the Nuevo León side,[82] which halted inspections at the Laredo–Colombia Solidarity International Bridge.

[84] Recognizing the increased demand due to nearshoring, García initiated plans to expand the Laredo–Colombia Solidarity International Bridge by adding more lanes to accommodate the growing number of trucks.

[85] In March 2022, in response to the low water levels in Nuevo León's three main reservoirs, García's administration implemented the Agua para todos (lit.

[92] On 17 June 2024, García warned residents of an approaching tropical cyclone, urging caution for those near rivers and reservoirs and noting potential dam floodgate openings.

[94] During the storm, García urged residents to stay home and issued an executive order on the night of 19 June suspending public transport and movement until the next day.

[95] On 25 June, García declared a state of emergency for Nuevo León, estimating the damages at around MX$1.5 billion, primarily in Santiago and Cadereyta Jiménez.

[97] Portions of Morones Prieto and Constitución, two avenues parallel to the Santa Catarina River [es], were closed due to erosion damage and were scheduled to reopen by the start of the next school year.

García disagreed with all the proposed candidates and vetoed de la Garza,[100] later appealing the list to the Supreme Court, citing irregularities in the selection process.

[105] This decision was appealed by García and quickly overturned by the Supreme Court, ruling that Arce had not met the criminal background check requirement.

[109] Shortly after receiving the list, García issued a veto,[110] after which the state congress unanimously appointed Javier Flores Saldívar as attorney general in the early hours of 18 February.

[111] Due to the withholding of the budget and the failure to publish several decrees passed by the legislature, on 31 January 2023, the state congress initiated impeachment proceedings against García, with the governor ordered to testify on 10 February.

[116] In October 2023, García requested a six-month leave, effective 2 December, to run in the 2024 presidential election, proposing Javier Navarro Velasco [es] as his replacement.

[119] On 29 November, the state congress convened to appoint Luis Enrique Orozco [es], the Deputy Attorney General, as interim governor.

"[128] In June 2020, he was accused of falsifying the documentation accrediting the Doctorate in Tax Law he obtained at ITAC University, a private educational center in the city of Monterrey.

[141] Samuel García started dating social media influencer Mariana Rodríguez Cantú in 2015, and were married on 27 March 2020 in the Metropolitan Cathedral of Monterrey.