Samuel Harrison Greene (December 25, 1845 – September 7, 1920) was an American Baptist pastor, church leader, and university official.

In 1875, upon graduation from seminary, Greene became pastor of a Baptist church in Cazenovia, New York.

Under his leadership, the church grew to over 1700 members[2] and became a model of the Baptist Sunday School movement.

[3] In 1903, he gave a lecture to the Southern Baptist Theological Seminary on the Calvary's Sunday School program,[4] which grew to approximately 2300.

[3] The president of the convention was then New York Governor Charles Evans Hughes who joined Calvary in 1911 after he was appointed Associate Justice of the Supreme Court of the United States.