Samuel Jones Lee (November 27, 1844 – April 1, 1895) was an American Civil War veteran of the Confederacy, politician and lawyer from South Carolina.

He served as the first African-American Speaker of the South Carolina House of Representatives and was a committed member of the Republican Party.

Lee was noted for his oratory skills and legal acumen, with an unprecedented twenty-seven appearances before the state supreme court.

Despite this achievement, he is described by University of South Carolina academic Lewis W. Burke as having "left a trail of scandal in the wake of his political career."

In 1875, while serving as an Aiken County commissioner, Lee was convicted of issuing fraudulent checks and in 1877 he was indicted on various counts of public corruption; however, he was granted immunity from prosecution in exchange for his testimony against Francis Cardozo.