Samuel Kwame Amponsah is a Ghanaian politician, farmer and a member of the 3rd parliament of the 4th republic of Ghana.

He studied Mathematics and had his PhD at the Kwame Nkrumah University of Science and Technology.

[1] He is a member of the National Democratic Congress and a representative of the Mpohor-Wassa East constituency of the Western Region of Ghana.

[6] His political career began when he contested in the 2000 Ghanaian General elections and won on the ticket of the National Democratic Congress.

[7][1] He was elected over Patrick Somiah Ehomah an independent candidate, Peter Nwanwaan of the New Patriotic Party, Abraham Yankson of the Convention People's Party, Stephen Blay of the National Reformed Party, Richard Aduko Raqib of the People's National Convention and Patrick Tandoh Williams of the United Ghana Movement.