Samuel Legerwood Patterson (March 6, 1850 – September 14, 1908) was a North Carolina politician and farmer.

The son of Samuel F. Patterson and his wife, Phoebe Caroline, Patterson was born in 1850 at Palmyra, the family plantation in Caldwell County, North Carolina.

[1] He served in the state House of Representatives in 1891 and 1899 and in the North Carolina Senate in 1893.

Patterson was appointed commissioner of agriculture from 1895 to 1897, when he was removed by the fusion of Republicans and Populists that came to power that year.

[2] Patterson Hall at North Carolina State University is named in his honor.