He was the only son of Samuel Lee, haberdasher of small wares in Fish Street Hill, London.
He was elected proctor for 1651, objection on the ground of insufficient standing being overruled by the parliamentary visitors, and he was admitted 9 April 1651.
On the death of John Rowe (12 October 1677) he became joint pastor with Theophilus Gale of Howe's congregation in Baker's Court, Holborn.
The following year, on Gale's death, he removed to Newington Green, where he was minister of an independent congregation till 1686.
[1] Lee migrated to New England in 1686, and on the formation of a church at Bristol, Rhode Island was chosen minister on 8 May 1687.
For the sixth edition (Oxford, 1662) he further supplied a treatise De Antiquitate Academiæ Oxoniensis, and Tractatulus ad Periodum Julianum spectans, both in the name of the printer H. Hall, and continued the work to that year.
He published a collection of thirty sermons by John Rowe, under the title of Emmanuel, or the Love of Christ, London, 1680.
[1] In his will Lee left property to his wife Martha, and books and manuscripts to his four daughters, Rebecca, Anna, Lydia, and Elizabeth.