Loizou was also a part of Parramatta's SG Ball team at 16 years of age winning their best and fairest award in 2019.

In 2021, Loizou started training with Parramatta's first grade squad, playing for their Jersey Flegg team and appearing in two games for NSW Cup.

In round 25 2021, Loizou made his NRL debut for Parramatta off the bench against the Penrith Panthers at Cbus Super Stadium in a 6–40 loss.

[5] On 21 November 2023, it was announced by the Wests Tigers that they had offered Loizou a train and trial deal ahead of the 2024 NRL season.

[6] After failing to secure a contract with the Wests Tigers, Loizou returned to the Parramatta team ahead of the 2024 NRL season.