Samuel Serle (1620–1683) was an English politician who sat in the House of Commons between 1656 and 1660.
He was commissioner for militia in March 1660 and became a major in April 1660.
[1] In 1679 Serle stood unsuccessfully for parliament again and became commissioner for assessment.
[1] Serle died at the age of 63 and was buried at Honiton on 2 February 1683.
[1] Serle married Mary and had ten sons and two daughters.