Samuel Tweedy (March 8, 1776 – July 1, 1868) was a United States representative from Connecticut.
Born at Nine Partners, New York in 1776, he later moved to Danbury, Connecticut.
Tweedy held many local offices before being elected as an Anti-Jacksonian to the Twenty-third Congress (March 4, 1833 – March 3, 1835).
He died in Danbury, Connecticut, aged 92.
He was buried in Wooster Cemetery.