Samuel Williams Reynolds (August 11, 1890 – March 20, 1988) was a Republican United States Senator from Nebraska.

During World War I, Reynolds served in the United States Army Air Service.

He later became a colonel and served as the director of the Army Specialist Corps in Omaha from 1942 to 1943.

In 1954, Reynolds was appointed by Governor Robert B. Crosby to the United States Senate to fill the open seat caused by the death of Hugh Butler.

He declined to run for the office that year and resumed selling coal.