[2] At present, the shrine is located on a low plateau on the left bank of the Sagami River, about seven kilometers inland in the central southern part of Kanagawa Prefecture; however, during the Yayoi period, it was located on the shore of an inlet of Sagami Bay which extended far inland from the present shoreline.

The ancient Tōkaidō highway crossed the Sagami River passed the east side of Samukawa Shrine.

Takeda Shingen visited the shrine and donated a kabuto helmet and sword to pray for victory when he attacked Odawara Castle in October 1569.

The shrine is a five-minute walk from Miyayama Station on the JR East Sagami Line.

During the Setsubun festival in February, illuminated paper figures are hung from the main gate in a style similar to that of the Nebuta in Aomori Prefecture.