The church of San Clemente is an ancient Roman Catholic church located near the Piazza del Foro, in central Brescia, region of Lombardy, Italy.

A church at the site is documented by 954, and was initially attached to the adjacent Benedictine monastery.

Further reconstructions occurred, with the latest which gave the present façade in 1800 under the architect Rodolfo Vantini.

The interior of the portico has a damaged fresco of Pope Clement I with Christ and saints.

The church contains a number of masterpieces by Moretto, including: The church also has a fresco of a Resurrection with St. Clement and Teresa painted by Il Romanino, a contemporary of Moretto.