San Domenico is a Baroque-style, Roman Catholic church and monastery located on via Matteo Raeli facing Piazza XVI Maggio in the town of Noto (province of Syracuse) in the region of Sicily, Italy.
The concave facade is rich in projecting columns, doric at the base and ionic in the second story.
The third altar to the left depicts a sculpted crucifixion with scenes of the Passion.
Others depict a St Dominic receiving the Holy Spirit and a Madonna of the Rosary (1712) by Vito D’Anna.
The main altar has a depiction of the Madonna of the Rosary in a gilded wooden ciborium designed by Antonio Basile.